Xylobiose, an alternative sweetener, ameliorates diabetes-related metabolic changes by regulating hepatic lipogenesis and miR-122a/33a in db/db Mice

Agriculture & Biology

• sweeteners 65%
• lipogenesis 64%
• mitogen-activated protein kinase 58%
• diabetes 57%
• sterols 38%
• liver 31%
• mice 30%
• binding proteins 23%
• superoxide dismutase 21%
• chemokine CCL2 20%
• cholesterol 20%
• glycohemoglobin 20%
• peroxisome proliferator-activated receptors 19%
• glucose tolerance 18%
• tumor necrosis factors 18%
• xylooligosaccharides 17%
• fatty-acid synthase 17%
• noninsulin-dependent diabetes mellitus 17%
• acetyl-CoA carboxylase 16%
• ABC transporters 15%
• interleukin-1 15%
• prebiotics 15%
• disaccharides 15%
• interleukin-6 14%
• anti-inflammatory activity 14%
• blood glucose 13%
• microRNA 13%
• fasting 13%
• glutathione peroxidase 12%
• xylose 12%
• cytokines 12%
• public health 12%
• insulin 11%
• phosphorylation 11%
• catalase 10%
• triacylglycerols 10%
• oxidative stress 10%
• sucrose 9%
• gene expression 8%
• diet 6%

Medicine & Life Sciences

• xylobiose 100%
• Sweetening Agents 74%
• Lipogenesis 66%
• Liver 27%
• Steroid 12-alpha-Hydroxylase 21%
• xylooligosaccharide 10%
• Sterol Regulatory Element Binding Protein 2 9%
• Cholesterol 7-alpha-Hydroxylase 8%
• superoxide dismutase 2 8%
• Hydroxymethylglutaryl CoA Reductases 8%
• Sterol Regulatory Element Binding Protein 1 8%
• Acetyl-CoA Carboxylase 8%
• Xylose 7%
• Fatty Acid Synthases 7%
• Disaccharides 7%
• Prebiotics 7%
• Superoxide Dismutase-1 7%
• Peroxisome Proliferator-Activated Receptors 7%
• ATP-Binding Cassette Transporters 7%
• Mitogen-Activated Protein Kinase 3 6%
• JNK Mitogen-Activated Protein Kinases 6%
• Mitogen-Activated Protein Kinase 1 6%
• Chemokine CCL2 6%
• Glutathione Peroxidase 6%
• Heat-Shock Proteins 6%
• p38 Mitogen-Activated Protein Kinases 6%
• Glucose Tolerance Test 6%
• Interleukin-1 5%
• Sucrose 5%
• Catalase 5%
• Protein Kinases 5%
• LDL Cholesterol 5%
• MicroRNAs 5%
• Blood Glucose 4%
• Area Under Curve 4%
• Triglycerides 4%
• Fasting 4%
• Interleukin-6 4%
• Type 2 Diabetes Mellitus 4%
• Anti-Inflammatory Agents 4%
• Oxidative Stress 4%
• Public Health 4%
• Tumor Necrosis Factor-alpha 4%
• Phosphorylation 4%
• Diet 4%
• Insulin 4%
• Glucose 3%
• Cytokines 3%
• Gene Expression 3%
• Messenger RNA 3%