Vitamin D deficiency and suicidal ideation: A cross-sectional study of 157,211 healthy adults

Sun Young Kim, Sang Won Jeon, Weon Jeong Lim, Kang Seob Oh, Dong Won Shin, Sung Joon Cho, Jae Hyun Park, Young Hwan Kim, Young Chul Shin

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Objectives: Vitamin D deficiency has been reported to be associated with various neuropsychiatric disorders. However, there are few studies addressing deficient vitamin D levels and suicidal ideation. Methods: Serum vitamin D of 157,211 Korean adult participants were measured using electrochemiluminescence immunoassay. A self-reported questionnaire was used to assess whether participants experienced suicidal ideation. Logistic regression model was used to estimate the odds ratio (OR) of suicidal ideation according to vitamin D levels. The regression was adjusted for a range of covariates. Results: Compared with sufficient vitamin D levels (≥20 ng/mL), deficient vitamin D levels (<10 ng/mL) were significantly associated with the risk of suicidal ideation (OR = 1.138, 95% Cl = 1.027–1.262). However, the OR of suicidal ideation was not significantly different between the vitamin D insufficient group (10–19.99 ng/mL) and sufficient group (≥20 ng/mL) (OR = 0.988, 95% Cl = 0.932–1.047). Conclusion: Deficient vitamin D levels were significantly associated with the risk of suicidal ideation. However, the risk of suicidal ideation was not significantly different between the vitamin D insufficient group and sufficient group.

Original languageEnglish
Article number110125
JournalJournal of Psychosomatic Research
Volume134
DOIs
StatePublished - Jul 2020

Keywords

  • Healthy adults
  • Suicidal ideation
  • Vitamin D

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