Visible-Light-Induced Arylthiofluoroalkylations of Unactivated Heteroaromatics and Alkenes

Yeojin Choi, Chunghyeon Yu, Jun Soo Kim, Eun Jin Cho

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

Visible-light-induced arylthiofluoroalkylations of unactivated heteroaromatics and alkenes have been developed utilizing readily available arylthiofluoroalkyl sources. This method enables simultaneous installation of sulfur and fluoroalkyl moieties, two important functional groups, which demonstrates its potential use for late-stage modifications in the synthesis of functional molecules. This method can be easily utilized to fine-tune the properties of lead molecules in drug development by controlling the number of fluorine atoms in the reagents.

Original languageEnglish
Pages (from-to)3246-3249
Number of pages4
JournalOrganic Letters
Volume18
Issue number13
DOIs
StatePublished - 1 Jul 2016

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