Valuation of EQ-5D-5L health states: a comparison of seven Asian populations

Pei Wang, Gordon G. Liu, Min woo Jo, Frederick Dermawan Purba, Zhihao Yang, Mihir Gandhi, Juntana Pattanaphesaj, Jeonghoon Ahn, Eliza Lai yi Wong, Arsul A. Shafie, Jan J.V. Busschbach, Nan Luo

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Objectives: To compare the time trade-off (TTO) utility values of EQ-5D-5L health states elicited from different general populations in Asia. Methods: We analyzed the TTO data from seven Asian EQ-5D-5L valuation studies in which utility values of 86 EQ-5D-5L health states were elicited from general population samples. An eight-parameter multiplicative regression model including five dimension parameters (mobility [MO], self-care, usual activities [UA], pain/discomfort, anxiety/depression) and three level parameters (level 2 [L2], level 3 [L3], and level 4 [L4]) was used to model the data from each of the populations. The model coefficients were compared to understand how the valuations of EQ-5D-5L health states differ. Results: For dimension parameters, Korea and Indonesia generally had the highest and lowest values among the populations, respectively; UA and MO commonly had the highest and lowest values among the parameters, respectively. For level parameters, Singapore and Korea generally had the highest and lowest values, respectively; L2 showed less variance compared to L3 and L4. Koreans, Indonesians, and Singaporeans appeared to have different health preferences compared with other populations. Conclusion: Utility values of EQ-5D-5L health states differ among Asian populations, suggesting that each health system should establish and use its own value set.

Original languageEnglish
Pages (from-to)445-451
Number of pages7
JournalExpert Review of Pharmacoeconomics and Outcomes Research
Issue number4
StatePublished - 4 Jul 2019


  • Asia
  • EQ-5D
  • comparison
  • utility
  • valuation


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