Valorization of lignocellulosic biomass for polyhydroxyalkanoate production: Status and perspectives

Yu Jung Sohn, Jina Son, Hye Jin Lim, Seo Hyun Lim, Si Jae Park

Research output: Contribution to journalReview articlepeer-review

30 Scopus citations


With the increasing concerns regarding climate, energy, and plastic crises, bio-based production of biodegradable polymers has become a dire necessity. Significant progress has been made in biotechnology for the production of biodegradable polymers from renewable resources to achieve the goal of zero plastic waste and a net-zero carbon bioeconomy. In this review, an overview of polyhydroxyalkanoate (PHA) production from lignocellulosic biomass (LCB) was presented. Having established LCB-based biorefinery with proper pretreatment techniques, various PHAs could be produced from LCB-derived sugars, hydrolysates, and/or aromatic mixtures employing microorganisms. This provides a clue for addressing the current environmental crises because “biodegradable polymers” could be produced from one of the most abundant resources that are renewable and sustainable in a “carbon-neutral process”. Furthermore, the potential future of LCB-to-non-natural PHA production was discussed with particular reference to non-natural PHA biosynthesis methods and LCB-derived aromatic mixture biofunnelling systems.

Original languageEnglish
Article number127575
JournalBioresource Technology
StatePublished - Sep 2022

Bibliographical note

Funding Information:
This work is supported by the Development of next-generation biorefinery platform technologies for leading bio-based chemicals industry project (2022M3J5A1056072) and by Development of platform technologies of microbial cell factories for the next-generation biorefineries project (2022M3J5A1056117) from National Research Foundation supported by the Korean Ministry of Science and ICT and the Basic Science Research Program (NRF-2020R1F1A1070249).

Publisher Copyright:
© 2022 Elsevier Ltd


  • Biodegradable polymer
  • Carbon–neutral
  • Lignocellulosic biomass
  • Polyhydroxyalkanoates
  • Valorization


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