Usefulness of 8 kDa protein of Fasciola hepatica in diagnosis of fascioliasis.

Kwangsig Kim, Hyun Jong Yang, Young Bae Chung

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

This study was designed to detect and evaluate an antigenicity of low molecular weight proteins of Fasciola hepatica in fascioliasis. Low molecular weight protein of F. hepatica was purified by ammonium sulfate precipitation and Sephacryl S-100 HR gel filtration. The protein obtained was estimated to be 8 kDa on 7.5-15% gradient sodium dodecyl sulfate gel electrophoresis. Immunoblotting studies showed that the 8 kDa protein reacted with human fascioliasis sera, but not other trematodiasis sera. This result suggests that the 8 kDa protein of F. hepatica is one of diagnostic antigens in human fascioliasis without cross-reaction with other human trematodiasis.

Original languageEnglish
Pages (from-to)121-123
Number of pages3
JournalThe Korean journal of parasitology
Volume41
Issue number2
DOIs
StatePublished - Jun 2003

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