Use of fim-1 to study the role protein kinase C in T-cell polarization

Martin Poenie; Christine Legler; Tom Morgan; Chii Shiarng Chen; Jong Ran Lee

Use of fim-1 to study the role protein kinase C in T-cell polarization

Martin Poenie, Christine Legler, Tom Morgan, Chii Shiarng Chen, Jong Ran Lee

Department of Life Science

Research output: Contribution to conference › Paper › peer-review

Abstract

The protein kinase C (PKC)-dependent association between talin and the membrane integrin, LFA-1 in CTL-target conjugates has been studied. Two possible mechanisms for directing talin to the target site are implied for the colocalization of PKC, talin and LFA-1. One is simply by binding to LFA-1 and the other through the localized activation of PKC. These two possibilities are investigated.

Original language	English
Pages	172-173
Number of pages	2
State	Published - 1994
Event	Proceedings of the 52nd Annual Meeting of the Microscopy Society of America - New Orleans, LA, USA Duration: 31 Jul 1994 → 5 Aug 1994

Conference

Conference	Proceedings of the 52nd Annual Meeting of the Microscopy Society of America
City	New Orleans, LA, USA
Period	31/07/94 → 5/08/94

Cite this

@conference{a3ff2be9f1ee43af92ded7e897c75087,

title = "Use of fim-1 to study the role protein kinase C in T-cell polarization",

abstract = "The protein kinase C (PKC)-dependent association between talin and the membrane integrin, LFA-1 in CTL-target conjugates has been studied. Two possible mechanisms for directing talin to the target site are implied for the colocalization of PKC, talin and LFA-1. One is simply by binding to LFA-1 and the other through the localized activation of PKC. These two possibilities are investigated.",

author = "Martin Poenie and Christine Legler and Tom Morgan and Chen, {Chii Shiarng} and Lee, {Jong Ran}",

year = "1994",

language = "English",

pages = "172--173",

note = "Proceedings of the 52nd Annual Meeting of the Microscopy Society of America ; Conference date: 31-07-1994 Through 05-08-1994",

}

TY - CONF

T1 - Use of fim-1 to study the role protein kinase C in T-cell polarization

AU - Poenie, Martin

AU - Legler, Christine

AU - Morgan, Tom

AU - Chen, Chii Shiarng

AU - Lee, Jong Ran

PY - 1994

Y1 - 1994

N2 - The protein kinase C (PKC)-dependent association between talin and the membrane integrin, LFA-1 in CTL-target conjugates has been studied. Two possible mechanisms for directing talin to the target site are implied for the colocalization of PKC, talin and LFA-1. One is simply by binding to LFA-1 and the other through the localized activation of PKC. These two possibilities are investigated.

AB - The protein kinase C (PKC)-dependent association between talin and the membrane integrin, LFA-1 in CTL-target conjugates has been studied. Two possible mechanisms for directing talin to the target site are implied for the colocalization of PKC, talin and LFA-1. One is simply by binding to LFA-1 and the other through the localized activation of PKC. These two possibilities are investigated.

UR - http://www.scopus.com/inward/record.url?scp=0028736904&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:0028736904

SP - 172

EP - 173

T2 - Proceedings of the 52nd Annual Meeting of the Microscopy Society of America

Y2 - 31 July 1994 through 5 August 1994

ER -

Use of fim-1 to study the role protein kinase C in T-cell polarization

Abstract

Conference

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