The protein kinase C (PKC)-dependent association between talin and the membrane integrin, LFA-1 in CTL-target conjugates has been studied. Two possible mechanisms for directing talin to the target site are implied for the colocalization of PKC, talin and LFA-1. One is simply by binding to LFA-1 and the other through the localized activation of PKC. These two possibilities are investigated.
|Number of pages||2|
|State||Published - 1994|
|Event||Proceedings of the 52nd Annual Meeting of the Microscopy Society of America - New Orleans, LA, USA|
Duration: 31 Jul 1994 → 5 Aug 1994
|Conference||Proceedings of the 52nd Annual Meeting of the Microscopy Society of America|
|City||New Orleans, LA, USA|
|Period||31/07/94 → 5/08/94|