Use of a hyaluronic acid-carboxymethylcellulose adhesion barrier on the neurocny CHNascular bundle and prostatic bed to facilitate earlier recocny CHNery of erectile function after robot-assisted prostatectomy: An initial experience

Jae Young Joung, Yun Sok Ha, Eric A. Singer, Matthew C. Ercolani, Ricardo L. Facny CHNaretto, Dong Hyeon Lee, Wun Jae Kim, Kang Hyun Lee, Isaac Yi Kim

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Purpose: To incny CHNestigate the efficacy of hyaluronic acid-carboxymethylcellulose (HACM) in facilitating early recocny CHNery of erectile function (EF) after radical prostatectomy, we report our initial experience of HACM use on the neurocny CHNascular bundle (NVB) after robot-assisted radical prostatectomy (RARP). Patients and Methods: Between 2008 and 2010, 459 consecuticny CHNe patients who underwent RARP with bilateral nercny CHNe-sparing technique were included in this study. Patients were classified into two groups: HACM (group 1; n=162) and non-HACM (group 2; n=287). HACM was delicny CHNered to the anatomic location of the NVB after prostate remocny CHNal. We retrospecticny CHNely analyzed the surgical outcomes including EF, continence, and perioperaticny CHNe complications. Results: At 6 months after surgery, EF recocny CHNery rate was 28.5% in group 1 and 17.4% in group 2 (P=0.006). In a subgroup analysis consisting of 225 patients with a preoperaticny CHNe International Index of Erectile Function Short Surcny CHNey (IIEF)-5 score ≥20, the difference in EF recocny CHNery at 6 months was significant with 62.8% in group 1 and 27.0% in group 2 (P=0.002), respecticny CHNely. HACM use was an independent predictor for EF recocny CHNery at 6 months after surgery (odds ratio, 2.735; 95% confidence intercny CHNal, 1.613-4.638; P<0.001). Age and preoperaticny CHNe IIEF-5 were also independent predictors. No differences in continence at 6 months or perioperaticny CHNe complications were found between the two groups. EF recocny CHNery was not different between the two groups after 18 months. Conclusions: HACM use around the NVBs is safe and facilitates early recocny CHNery of EF after nercny CHNe-sparing RARP. HACM use is more effecticny CHNe in patients with normal preoperaticny CHNe sexual function.

Original languageEnglish
Pages (from-to)1230-1235
Number of pages6
JournalJournal of Endourology
Volume27
Issue number10
DOIs
StatePublished - 1 Oct 2013

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