Understanding of the Lower Extremity Motor Recovery After First-Ever Ischemic Stroke

Hyun Haeng Lee, Min Kyun Sohn, Deog Young Kim, Yong Il Shin, Gyung Jae Oh, Yang Soo Lee, Min Cheol Joo, So Young Lee, Min Keun Song, Junhee Han, Jeonghoon Ahn, Young Hoon Lee, Won Hyuk Chang, Soo Mi Choi, Seon Kui Lee, Jongmin Lee, Yun Hee Kim

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Background: We aimed to verify the validity of the proportional recovery model for the lower extremity. Methods: We reviewed clinical data of patients enrolled in the Korean Stroke Cohort for Functioning and Rehabilitation between August 2012 and May 2015. Recovery proportion was calculated as the amount of motor recovery over initial motor impairment, measured as the Fugl-Meyer Assessment of Lower Extremity score. We used the logistic regression method to model the probability of achieving the full Fugl-Meyer Assessment of Lower Extremity score, whereby we considered the ceiling effect of the score. To show the difference in the prevalence of achieving the full Fugl-Meyer Assessment of Lower Extremity score between 3 and 6 months poststroke, we constructed a marginal model through the generalized estimating equation method. We also performed the propensity score matching analysis to show the dependency of recovery proportion on the initial motor deficit at 3 and 6 months poststroke. Results: We evaluated 1085 patients. The recovery proportions at 3 and 6 months poststroke were 0.67±0.42 and 0.75±0.39, respectively. A 1-unit decrease in the initial neurological impairment and the age at stroke onset increased the probability of achieving the full Fugl-Meyer Assessment of Lower Extremity score, which occurred at both 3 and 6 months poststroke. The prevalence of those who reach full lower limb motor recovery differs significantly between 3 and 6 months poststroke. We also found out that the recovery proportion at both 3 and 6 months poststroke is determined by the initial motor deficits of the lower limb. These results are not consistent with the proportional recovery model. Conclusions: Our results demonstrated that the proportional recovery model for the lower limb is invalid.

Original languageEnglish
Pages (from-to)3164-3172
Number of pages9
JournalStroke
Volume53
Issue number10
DOIs
StatePublished - 1 Oct 2022

Bibliographical note

Funding Information:
This work was supported by the Research Program funded by Korea Disease Control and Prevention Agency (2019E320202).

Publisher Copyright:
© 2022 Lippincott Williams and Wilkins. All rights reserved.

Keywords

  • brain
  • ischemia
  • ischemic stroke
  • lower extremity
  • recovery of function

Fingerprint

Dive into the research topics of 'Understanding of the Lower Extremity Motor Recovery After First-Ever Ischemic Stroke'. Together they form a unique fingerprint.

Cite this