Two new Scalaranes from a Korean marine sponge Spongia sp

Inho Yang, Sang Jip Nam, Heonjoong Kang

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5 Scopus citations


Intensive chemical investigation of Korean marine sponge Spongia sp. has led to the isolation of two new scalaranes. The planar structures of the new compounds 1 and 2 were determined through 1D and 2D NMR spectral data analysis, while the relative stereochemistry of the compounds was determined based on the analysis of 1H-1H coupling constants and NOESY spectroscopic data. Compounds 1 and 2 did not display any significant biological activities on farnesoid X-activated receptor (FXR) in co-transfection assay.

Original languageEnglish
Pages (from-to)289-292
Number of pages4
JournalNatural Product Sciences
Issue number4
StatePublished - 2015

Bibliographical note

Publisher Copyright:
© 2015, Korean Society of Pharmacognosy. All rights reserved.


  • Korean sponge
  • Marine natural product
  • Scalarane
  • Sesterpenoid
  • Spongia sp


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