Two new Scalaranes from a Korean marine sponge Spongia sp

Inho Yang, Sang Jip Nam, Heonjoong Kang

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Intensive chemical investigation of Korean marine sponge Spongia sp. has led to the isolation of two new scalaranes. The planar structures of the new compounds 1 and 2 were determined through 1D and 2D NMR spectral data analysis, while the relative stereochemistry of the compounds was determined based on the analysis of 1H-1H coupling constants and NOESY spectroscopic data. Compounds 1 and 2 did not display any significant biological activities on farnesoid X-activated receptor (FXR) in co-transfection assay.

Original languageEnglish
Pages (from-to)289-292
Number of pages4
JournalNatural Product Sciences
Volume21
Issue number4
DOIs
StatePublished - 2015

Bibliographical note

Publisher Copyright:
© 2015, Korean Society of Pharmacognosy. All rights reserved.

Keywords

  • Korean sponge
  • Marine natural product
  • Scalarane
  • Sesterpenoid
  • Spongia sp

Fingerprint

Dive into the research topics of 'Two new Scalaranes from a Korean marine sponge Spongia sp'. Together they form a unique fingerprint.

Cite this