Two Cases of Orofacial Granulomatosis

Bo Ram Kwon, Min Jung Choi, Ji Yeon Byun, You Won Choi, Hae Young Choi

Research output: Contribution to journalArticlepeer-review


Orofacial granulomatosis (OFG) is a rare chronic granulomatous disease of oral mucosa and maxillofacial region that clinically presents recurrent or persistent orofacial swelling. OFG may exist as an integration of the spectrum of various disorders, including Melkersson-Rosenthal syndrome, granulomatous cheilitis, Crohn’s disease, sarcoidosis, infectious diseases and delayed hypersensitivity reaction to food additives, dental materials. Precise etiology is not yet to be elucidated. Herein, we report two rare cases of orofacial granulomatosis who presented similar clinical manifestation of lip swelling but was diagnosed as a sarcoidosis and as a granulomatous cheilitis. (Korean J Dermatol 2020;58(3):191∼195)

Original languageEnglish
Pages (from-to)191-195
Number of pages5
JournalKorean Journal of Dermatology
Issue number3
StatePublished - 2020

Bibliographical note

Publisher Copyright:
© 2020 Korean Dermatological Association. All rights reserved.


  • Granulomatous cheilitis
  • Melkersson-Rosenthal syndrome
  • Orofacial granulomatosis
  • Sarcoidosis


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