Tunneling Effect That Changes the Reaction Pathway from Epoxidation to Hydroxylation in the Oxidation of Cyclohexene by a Compound I Model of Cytochrome P450

Engineering & Materials Science

• Cytochrome P-450 Enzyme System 100%
• Hydroxylation 97%
• Epoxidation 93%
• Oxidation 47%
• Rate constants 33%
• Temperature 21%
• Chemical activation 16%
• Porphyrins 15%
• Hydrogen 14%
• Energy barriers 13%
• Density functional theory 13%
• Positive ions 11%
• Atoms 9%
• Iron 8%

Physics & Astronomy

• epoxidation 94%
• cytochromes 70%
• oxidation 39%
• activation 8%
• temperature 7%
• porphyrins 6%
• hydrogen atoms 5%
• cations 4%
• density functional theory 4%
• iron 3%
• temperature dependence 3%
• products 3%
• energy 1%

Chemical Compounds

• Cytochrome P450 58%
• Cyclohexene 56%
• Tunneling 54%
• Oxidation Reaction 24%
• Rate Constant 17%
• Chemical Activation 10%
• Energy Barrier 8%
• Hydrogen Atom 7%
• Porphyrin 7%
• Density Functional Theory 5%