Tumor-targeting gold particles for dual computed tomography/optical cancer imaging

In Cheol Sun, Dae Kyung Eun, Heebeom Koo, Chang Yong Ko, Han Sung Kim, Dong Kee Yi, Kuiwon Choi, Ick Chan Kwon, Kwangmeyung Kim, Cheol Hee Ahn

Research output: Contribution to journalArticlepeer-review

111 Scopus citations


Double spotlight: A dual imaging probe with gold nanoparticles (AuNPs) for computed tomography (CT) and optical imaging exhibits have been developed (see picture). The excellent stability, tumor targeting ability, enhanced X-ray absorption, and matrix metalloproteinase (MMP) activatable fluorescence recovery was achieved by surface modification of AuNPs with glycol chitosan and fluorescent MMP peptide probes.

Original languageEnglish
Pages (from-to)9348-9351
Number of pages4
JournalAngewandte Chemie - International Edition
Issue number40
StatePublished - 26 Sep 2011


  • computed tomography
  • gold
  • imaging agents
  • nanoparticles


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