TRUE test in patients with contact dermatitis: A multicenter study

Yeon Ju Hong, Hae Young Choi, Kea Jeung Kim, Ga Young Lee, Do Won Kim, Seong Jin Kim, Soo Chan Kim, Young Suck Ro, Kee Chan Moon, Mi Youn Park, Sang Wook Son, Jeong Hyun Shin, Jun Mo Yang, Hee Chul Eun, Min Geol Lee, Cheol Heon Lee, Chang Kwun Hong

Research output: Contribution to journalArticlepeer-review

24 Scopus citations


Background: The TRUE test is a commercially available ready-to-apply patch test widely used in many countries, but no large-scale study is available on the TRUE test in Korea. Objective: The purpose of this study was to analyze the type, frequency, and changes in the common contact allergens in Korea using the TRUE test. Methods: From January 2009 to March 2010, TRUE tests were performed on patients with contact dermatitis at the Departments of Dermatology of 15 hospitals. The epidemiological findings of patients, and the results of the patch tests were analyzed. Results: In total, 795 patch tested cases (246 males, 549 females) were compiled and analyzed. The oldest age distribution was the third decade in both males and females, and housewives and office-workers were the most common jobs, comprising 29.7% and 19.8% of the occupations, respectively. Overall, 65.1% of patients had at least one positive reaction, and the most common allergens were nickel sulfate (34.1%), thimerosal (12.6%), cobalt chloride (11.1%), and p-phenylenediamine (8.4%), in order of frequency. A univariate analysis of multiple variables including age, gender, occupation, and affected sites was conducted and a comparison with a previous multicenter study was also analyzed. Conclusion: These results provide the basis for use of the TRUE test in patients with contact dermatitis in Korea.

Original languageEnglish
Pages (from-to)661-669
Number of pages9
JournalKorean Journal of Dermatology
Issue number8
StatePublished - Aug 2011


  • Contact dermatitis
  • Patch test
  • TRUE test


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