Trends in incidence and survival of esophageal cancer in Korea: Analysis of the Korea central cancer registry database

Aesun Shin, Young Joo Won, Hye Kyung Jung, Hyun Joo Kong, Kyu Won Jung, Chang Mo Oh, Sunho Choe, Jihyun Lee

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

Background and Aim: The diagnostic and therapeutic modalities of esophageal cancer have recently improved in Asia, and its prognosis is expected to change. This study provides a population-based report on the epidemiology of esophageal cancer in Korea. Methods: Cancer incidence data from 1999 to 2013 were obtained from the Korea Central Cancer Registry, covering the entire population. Age-standardized incidence rates and annual percent changes were calculated according to subsites and histological types. Five-year relative survival rates were estimated for cases diagnosed between 1993 and 2013. Relative excess rates were compared between patients diagnosed from 2009 to 2013 and 2006 to 2008. Results: The age-standardized incidence rates decreased from 8.8 per 100 000 populations in 1999 to 5.9 in 2013 with an annual percent change of 2.6% in men and 2.2% in women. The most common histological type was squamous cell carcinoma, accounting for 90.2% of all esophageal cancers in 2013, followed by adenocarcinomas (3.1%), and their incidences decreased. The proportion of localized and regional cancer tended to increase compared with that of distant cancer. Five-year relative survival of squamous cell carcinoma improved from 12.1% (1993–1995) to 34.6% (2009–2013). Relative excess rate was 0.72 (95% confidence interval 0.65–0.80) in localized stage and 0.88 (95% confidence interval, 0.82–0.95) in regional stage comparing patients diagnosed from 2009 to 2013 and 2006 to 2008. Conclusions: The incidence of esophageal cancer has decreased in Korea for the past 15 years, and 5-year survival rates have improved significantly. These increases may be attributable to more effective detection of early-stage disease.

Original languageEnglish
Pages (from-to)1961-1968
Number of pages8
JournalJournal of Gastroenterology and Hepatology (Australia)
Volume33
Issue number12
DOIs
StatePublished - Dec 2018

Keywords

  • Cancer incidence
  • Cancer registry
  • Esophageal cancer
  • Survival rates

Fingerprint

Dive into the research topics of 'Trends in incidence and survival of esophageal cancer in Korea: Analysis of the Korea central cancer registry database'. Together they form a unique fingerprint.

Cite this