Trace of evolutionary evidence by analyzing clustering information of metabolic pathways in eukaryotes

Arang Rhie, Myungha Jang, Hyun Seok Park

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Alternative pathways in genetic and molecular pathways are suggesting evidence of evolution. By clustering and analyzing the metabolic pathways of 61 species in 5 classes within eukaryotes based on its topology, we obtained an interesting result that implies this evolutionary evidence. After grouping reactions along their connectivity, the results showed that compounds in higher organisms were less clustered into loosely connected groups. This implies that higher organisms have evolved in alternative pathways, giving traces of evolution.

Original languageEnglish
Title of host publication2010 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2010
Pages862-863
Number of pages2
DOIs
StatePublished - 2010
Event2010 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2010 - HongKong, China
Duration: 18 Dec 201021 Dec 2010

Publication series

Name2010 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2010

Conference

Conference2010 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2010
Country/TerritoryChina
CityHongKong
Period18/12/1021/12/10

Keywords

  • Alternative pathway
  • Comparative pathway study
  • Evolution
  • Metabolic pathway
  • Topology

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