Total synthesis of the L-hexoses

Soo Y. Ko, Albert W.M. Lee, Satoru Masamune, Lawrence A. Reed III, K. Barry Sharpless, Frederick J. Walker

Research output: Contribution to journalArticlepeer-review

131 Scopus citations

Abstract

Enantiomerically pure polyhydroxylated natural products are synthesized by using a reiterative two-carbon extension cycle consisting of four key transformations. The generality and efficiency of this methodology are demonstrated in the total synthesis of all eight L-hexoses.

Original languageEnglish
Pages (from-to)245-264
Number of pages20
JournalTetrahedron
Volume46
Issue number1
DOIs
StatePublished - 1990

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