@article{1585c5b8a3494a3da3b4fcce7c4c21ac,
title = "Total Synthesis of Hoiamide A Using an Evans-Tishchenko Reaction as a Key Step",
abstract = "The first total synthesis of neurotoxic cyclodepsipeptide hoiamide A (1) has been accomplished. The synthesis features the use of an Evans-Tishchenko fragment coupling between a five-stereogenic-center-containing β-hydroxyketone and a chiral aldehyde derived from threonine.",
author = "Yian Guo and Jingjing Zhou and Bowen Gao and Meng Zhao and Yan, {Jia Lei} and Zhengshuang Xu and Sun Choi and Tao Ye",
note = "Funding Information: We acknowledge financial support from the Shenzhen Peacock Plan (KQTD2015071714043444); the NSFC (21772009), (21272011); the SZSTIC (JCYJ20160527100424909), (JSGG20170414114147358); the GDNSF (2014B030301003); China Postdoctoral Science Foundation (2018M641059 to Y.G.); MSIT via NRF (NRF-2017R1A2B4010084, 2018R1A5A2025286; 2018M3A9A7057263); and Peng Cheng Scholar (to S.C.). This work was also inspired by the international and interdisciplinary environments of the JSPS Asian CORE Program, “Asian Chemical Biology Initiative. Publisher Copyright: Copyright {\textcopyright} 2019 American Chemical Society.",
year = "2019",
month = jul,
day = "5",
doi = "10.1021/acs.orglett.9b01735",
language = "English",
volume = "21",
pages = "5471--5474",
journal = "Organic Letters",
issn = "1523-7060",
publisher = "American Chemical Society",
number = "14",
}