Thermoresponsive micelles from oligopeptide-grafted cyclotriphosphazenes

(Figure Presented) Hard graft: Amphiphilic cyclic phosphazene trimers grafted with Hydrophobic oligopeptide (red) and hydrophilic methoxypolyethylene glycol (blue) show a variety of thermoresponsive properties including lower critical solution temperatures near body temperature. They form strong micelles in aqueous solution at an appropriate hydrophobic-to-hydrophilic balance.