Thermoresponsive micelles from oligopeptide-grafted cyclotriphosphazenes

Yong Joo Jun; Udaya S. Toti; Hye Young Kim; Ji Young Yu; Byeongmoon Jeong; Moo Jin Jun; Youn Soo Sohn

doi:10.1002/anie.200601108

Thermoresponsive micelles from oligopeptide-grafted cyclotriphosphazenes

Yong Joo Jun, Udaya S. Toti, Hye Young Kim, Ji Young Yu, Byeongmoon Jeong, Moo Jin Jun, Youn Soo Sohn

Department of Chemistry & Nanoscience

Research output: Contribution to journal › Article › peer-review

55 Scopus citations

Abstract

(Figure Presented) Hard graft: Amphiphilic cyclic phosphazene trimers grafted with Hydrophobic oligopeptide (red) and hydrophilic methoxypolyethylene glycol (blue) show a variety of thermoresponsive properties including lower critical solution temperatures near body temperature. They form strong micelles in aqueous solution at an appropriate hydrophobic-to-hydrophilic balance.

Original language	English
Pages (from-to)	6173-6176
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	45
Issue number	37
DOIs	https://doi.org/10.1002/anie.200601108
State	Published - 18 Sep 2006

Keywords

Amphiphiles
Drug delivery
Micelles
Oligopeptides
Phosphazenes

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10.1002/anie.200601108

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title = "Thermoresponsive micelles from oligopeptide-grafted cyclotriphosphazenes",

abstract = "(Figure Presented) Hard graft: Amphiphilic cyclic phosphazene trimers grafted with Hydrophobic oligopeptide (red) and hydrophilic methoxypolyethylene glycol (blue) show a variety of thermoresponsive properties including lower critical solution temperatures near body temperature. They form strong micelles in aqueous solution at an appropriate hydrophobic-to-hydrophilic balance.",

keywords = "Amphiphiles, Drug delivery, Micelles, Oligopeptides, Phosphazenes",

author = "Jun, {Yong Joo} and Toti, {Udaya S.} and Kim, {Hye Young} and Yu, {Ji Young} and Byeongmoon Jeong and Jun, {Moo Jin} and Sohn, {Youn Soo}",

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AU - Jun, Yong Joo

AU - Toti, Udaya S.

AU - Kim, Hye Young

AU - Yu, Ji Young

AU - Jeong, Byeongmoon

AU - Jun, Moo Jin

AU - Sohn, Youn Soo

PY - 2006/9/18

Y1 - 2006/9/18

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AB - (Figure Presented) Hard graft: Amphiphilic cyclic phosphazene trimers grafted with Hydrophobic oligopeptide (red) and hydrophilic methoxypolyethylene glycol (blue) show a variety of thermoresponsive properties including lower critical solution temperatures near body temperature. They form strong micelles in aqueous solution at an appropriate hydrophobic-to-hydrophilic balance.

KW - Amphiphiles

KW - Drug delivery

KW - Micelles

KW - Oligopeptides

KW - Phosphazenes

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DO - 10.1002/anie.200601108

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JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 37

ER -

Thermoresponsive micelles from oligopeptide-grafted cyclotriphosphazenes

Abstract

Keywords

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