Thermoresponsive micelles from oligopeptide-grafted cyclotriphosphazenes

Yong Joo Jun, Udaya S. Toti, Hye Young Kim, Ji Young Yu, Byeongmoon Jeong, Moo Jin Jun, Youn Soo Sohn

Research output: Contribution to journalArticlepeer-review

53 Scopus citations

Abstract

(Figure Presented) Hard graft: Amphiphilic cyclic phosphazene trimers grafted with Hydrophobic oligopeptide (red) and hydrophilic methoxypolyethylene glycol (blue) show a variety of thermoresponsive properties including lower critical solution temperatures near body temperature. They form strong micelles in aqueous solution at an appropriate hydrophobic-to-hydrophilic balance.

Original languageEnglish
Pages (from-to)6173-6176
Number of pages4
JournalAngewandte Chemie - International Edition
Volume45
Issue number37
DOIs
StatePublished - 18 Sep 2006

Keywords

  • Amphiphiles
  • Drug delivery
  • Micelles
  • Oligopeptides
  • Phosphazenes

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