The total synthesis of epibatidine

Soo Y. Ko, Joanne Lerpiniere, Ian D. Linney, Roger Wrigglesworth

Research output: Contribution to journalArticlepeer-review

41 Scopus citations


The synthesis of the potent analgesic alkaloid epibatidine 1, employing as the key step a singlet oxygen reaction with 1-(2-chloro-5-pyridyl)cyclohexa-2,4- diene 2, is described.

Original languageEnglish
Pages (from-to)1775-1776
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number15
StatePublished - 1994


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