The role of 18F-fluorodeoxyglucose positron emission tomography in the diagnosis, staging, and follow-up of cholangiocarcinoma

Chang Mo Moon, Seungmin Bang, Jae Bock Chung

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations

Abstract

18F-Fluorodeoxyglucose positron emission tomography ( 18FDG-PET) is a new diagnostic technique for the diagnosis and staging of cholangiocarcinoma. For diagnosis of a primary cholangiocarcinoma, 18FDG-PET seems to be helpful to discriminate between malignant and benign lesions. However, the accuracy of 18FDG-PET seems to be dependent on the anatomic location, growth pattern, and pathologic characteristics of the lesion. It has been proved that the accuracy of 18FDG-PET is limited to detection of extrahepatic, infiltrating, and mucinous cholangiocarcinomas. Due to its lower sensitivity, 18FDG-PET provides complementary rather than confirmative information in the diagnosis of regional lymph node metastasis. In contrast, it has high accuracy in detecting unsuspected distant metastases. The role of 18FDG-PET in detecting cancer recurrence, monitoring treatment response, and predicting prognosis is still controversial.

Original languageEnglish
Pages (from-to)e10-e17
JournalSurgical Oncology
Volume20
Issue number1
DOIs
StatePublished - Mar 2011

Keywords

  • Cholangiocarcinoma
  • Fluorodeoxyglucose
  • Positron emission tomography

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