The role of extracellular matrix in restenosis after percutaneous coronary intervention

Ick Mo Chung

doi:10.1016/j.ics.2003.11.008

The role of extracellular matrix in restenosis after percutaneous coronary intervention

Ick Mo Chung

Department of Internal Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Restenosis after percutaneous coronary intervention (PCI) might be a kind of wound healing reaction, involving at least two important processes, vascular remodeling and neointima formation. There is an accumulating amount of evidence to suggest that the dynamic modulation of the extracellular matrix (ECM) contributes significantly to restenosis by interacting with cells and matrices. In this brief review, the expression pattern of ECM and the possible role of these molecules in the restenosis process are discussed.

Original language	English
Pages (from-to)	414-417
Number of pages	4
Journal	International Congress Series
Volume	1262
Issue number	C
DOIs	https://doi.org/10.1016/j.ics.2003.11.008
State	Published - 1 May 2004

Keywords

Extracellular matrix
Hyaluronan
Neointima
Proteoglycan
Restenosis

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abstract = "Restenosis after percutaneous coronary intervention (PCI) might be a kind of wound healing reaction, involving at least two important processes, vascular remodeling and neointima formation. There is an accumulating amount of evidence to suggest that the dynamic modulation of the extracellular matrix (ECM) contributes significantly to restenosis by interacting with cells and matrices. In this brief review, the expression pattern of ECM and the possible role of these molecules in the restenosis process are discussed.",

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AB - Restenosis after percutaneous coronary intervention (PCI) might be a kind of wound healing reaction, involving at least two important processes, vascular remodeling and neointima formation. There is an accumulating amount of evidence to suggest that the dynamic modulation of the extracellular matrix (ECM) contributes significantly to restenosis by interacting with cells and matrices. In this brief review, the expression pattern of ECM and the possible role of these molecules in the restenosis process are discussed.

KW - Extracellular matrix

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KW - Proteoglycan

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The role of extracellular matrix in restenosis after percutaneous coronary intervention

Abstract

Keywords

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