The pharmacology of actoprotectors: Practical application for improvement of mental and physical performance

Sergiy Oliynyk, Seikwan Oh

Research output: Contribution to journalReview articlepeer-review

18 Scopus citations

Abstract

Actoprotectors are preparations that enhance body stability against physical loads without increasing oxygen consumption or heat production. Or, in short, actoprotectors are synthetic adaptogens with a significant capacity to improve physical performance. This paper explores the history of actoprotectors' development, their pharmacological properties, mechanism of action, and practical application to the improvement of mental and physical performance. A brief summary of the clinico-pharmacological characteristics of the main representatives of this class (bemitil and bromantane) is provided. Some other synthesized compounds, and even natural ones such as ginseng, also are regarded as potential actoprotectors, and these are treated herein as well. Actoprotectors, owing to their wide-ranging pharmacological activities, high efficiency and safety, can be applied under either normal or extreme conditions.

Original languageEnglish
Pages (from-to)446-456
Number of pages11
JournalBiomolecules and Therapeutics
Volume20
Issue number5
DOIs
StatePublished - Sep 2012

Keywords

  • Actoprotector
  • Asthenia
  • Bemitil
  • Bromantane
  • Mental work capacity

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