The model for end-stage liver disease score-based system predicts short term mortality better than the current child-turcotte-pugh score-based allocation system during waiting for deceased liver transplantation

Geun Hong, Kwang Woong Lee, Sukwon Suh, Tae Yoo, Hyeyoung Kim, Min Su Park, Youngrok Choi, Nam Joon Yi, Kyung Suk Suh

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

To adopt the model for end-stage liver disease (MELD) score-based system in Korea, the feasibility should be evaluated by analysis of Korean database. The aim of this study was to investigate the feasibility of the MELD score-based system compared with the current Child-Turcotte-Pugh (CTP) based-system and to suggest adequate cut-off to stratify waiting list mortality among Korean population. We included 788 adult patients listed in waiting list in Seoul National University Hospital from January 2008 to May 2011. The short-term survival until 6 months after registration was evaluated. Two hundred forty six (31.2%) patients underwent live donor liver transplantation and 353 (44.8%) patients were still waiting and 121 (15.4%) patients were dropped out due to death. Significant difference was observed when MELD score 24 and 31 were used as cut-off. Three-months survival of Status 2A was 70.2%. However, in Status 2A patients whose MELD score less than 24 (n= 82), 86.6% of patients survived until 6month. Furthermore, patients with high MELD score (≥ 31) among Status 2B group showed poorer survival rate (45.8%, 3-month) than Status 2A group. In conclusion, MELD score-based system can predict short term mortality better and select more number of high risk patients in Korean population.

Original languageEnglish
Pages (from-to)1207-1212
Number of pages6
JournalJournal of Korean Medical Science
Volume28
Issue number8
DOIs
StatePublished - 2013

Keywords

  • Liver diseases
  • Liver transplantation
  • Meld score
  • Mortality
  • Survival
  • Waiting lists

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