The limitations of endoscopic ultrasound-guided fine needle aspiration cytology in the diagnosis of pancreatic serous cystadenoma: A brief case report

Endoscopic ultrasound (EUS) fine needle aspiration (FNA) biopsy is commonly used in the diagnosis of pancreatic tumors. Although adenocarcinoma is the most commonly diagnosed primary pancreatic neoplasm, other neoplasms can also arise in this organ. For accurate diagnosis, pathologists must be familiar with the cytomorphology associated with all types of pancreatic tumors. Serous cystadenoma (SCA) is a rare, benign neoplasm that originates in the centro-acinar epithelium of the pancreas. Excluding any symptomatic or diagnostic uncertainty, patients presenting with SCA need no further management. Here, we report a case of pancreatic SCA that was suspected to be adenocarcinoma in preoperative test using EUS-guided FNA.