The lack of histological changes of CDMA cellular phone-based radio frequency on rat testis

Hae June Lee, Jeong Ki Pack, Tae Hong Kim, Nam Kim, Soo Yong Choi, Jae Seon Lee, Sung Ho Kim, Yun Sil Lee

Research output: Contribution to journalArticlepeer-review

48 Scopus citations

Abstract

We examined the histological changes by radiofrequency (RF) fields on rat testis, specifically with respect to sensitive processes such as spermatogenesis. Male rats were exposed to 848.5MHz RF for 12 weeks. The RF exposure schedule consisted of two 45-min RF exposure periods, separated by a 15-min interval. The whole-body average specific absorption rate (SAR) of RF was 2.0 W/kg. We then investigated correlates of testicular function such as sperm counts in the cauda epididymis, malondialdehyde concentrations in the testes and epididymis, frequency of spermatogenesis stages, germ cell counts, and appearance of apoptotic cells in the testes. We also performed p53, bcl-2, caspase 3, p21, and PARP immunoblotting of the testes in sham- and RF-exposed animals. Based on these results, we concluded that subchronic exposure to 848.5 MHz with 2.0 W/kg SAR RF did not have any observable adverse effects on rat spermatogenesis.

Original languageEnglish
Pages (from-to)528-534
Number of pages7
JournalBioelectromagnetics
Volume31
Issue number7
DOIs
StatePublished - Oct 2010

Keywords

  • 848.5 MHz
  • Rat spermatogenesis
  • RF exposure

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