The impact of a ventilator bundle on preventing ventilator-associated pneumonia: A multicenter study

Joong Sik Eom, Mi Suk Lee, Hee Kyung Chun, Hee Jung Choi, Sun Young Jung, Yeon Sook Kim, Seon Jin Yoon, Yee Gyung Kwak, Gang Bok Oh, Min Hyok Jeon, Sun Young Park, Hyun Sook Koo, Young Su Ju, Jin Seo Lee

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82 Scopus citations


Background For prevention of ventilator-associated pneumonia (VAP), a bundle approach was applied to patients receiving mechanical ventilation in intensive care units. The incidence of VAP and the preventive efficacy of the VAP bundle were investigated. Methods A quasi-experimental study was conducted in adult intensive care units of 6 university hospitals with similar VAP rates. We implemented the VAP bundle between March 2011 and June 2011, then compared the rate of VAP after implementation of the VAP bundle with the rate in the previous 8 months. Our ventilator bundle included head of bed elevation, peptic ulcer disease prophylaxis, deep venous thrombosis prophylaxis, and oral decontamination with chlorhexidine 0.12%. Continuous aspiration of subglottic secretions was an option. Results Implementation of the VAP bundle reduced the VAP rate from a mean of 4.08 cases per 1,000 ventilator-days to 1.16 cases per 1,000 ventilator-days. The incidence density ratio (rate) was 0.28 (95% confidence interval, 0.275-0.292). Conclusions Implementing the appropriate VAP bundle significantly decreased the incidence of VAP in patients with mechanical ventilation.

Original languageEnglish
Pages (from-to)34-37
Number of pages4
JournalAmerican Journal of Infection Control
Issue number1
StatePublished - Jan 2014

Bibliographical note

Funding Information:
This study was supported by the Korean Centers for Disease Control and Prevention .


  • Infection control
  • Intensive care units
  • Lung diseases


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