The HgCl2-promoted guanylation reaction: The scope and limitations

Catherine Levallet, Joanne Lerpiniere, Soo Y. Ko

Research output: Contribution to journalArticlepeer-review

130 Scopus citations

Abstract

The HgCl2-promoted guanylation reaction was studied with various substituted thiourea starting materials and the scope and limitations are presented. The process was found to be effective with thioureas containing at least one N-conjugated substituent. Such activating groups include N-carbonyl-(acyl, alkoxycarbonyl, carbamoyl, etc.), N-cyano-, N-sulfonyl-, and N-aryl- substituents.

Original languageEnglish
Pages (from-to)5291-5304
Number of pages14
JournalTetrahedron
Volume53
Issue number14
DOIs
StatePublished - 7 Apr 1997

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