The health-related quality-of-life of chronic obstructive pulmonary disease patients and disease-related indirect burdens

Hye Sook Choi, Dong Wook Yang, Chin Kook Rhee, Hyoung Kyu Yoon, Jin Hwa Lee, Seong Yong Lim, Yu Il Kim, Kwang Ha Yoo, Yong Il Hwang, Sang Haak Lee, Yong Bum Park

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Background/Aims: Many chronic obstructive pulmonary disease (COPD) patients have physical limitations. We investigated EuroQol five-dimensions five-level (EQ-5D-5L) of COPD patients to assess quality of life, and assessed indirect burden including time expenditure to visit doctor, home care rate, and caregiver related burden. Methods: We recruited 355 COPD patients according to severity of airflow limitation that severity was set at 10% mild, 40% moderate, 30% severe, and 20% very severe in two primary and 11 secondary/tertiary hospitals. Eligible patients were aged ≥ 40 years, who have been diagnosed with COPD for more than 1 year. Patients were recruited between June 2015 and October 2016. Results: The quality of life tended to decline with age, from mild to very severe impairment, as revealed by the EQ-5D-5L scores and the EQ visual analog scale. Family caregivers accompanied 22.6% of patients who visited outpatient clinics, and 25% of stage IV COPD patients. During emergency visits and hospitalization, this figure increased to > 60%. The home care rates were 28.5% for stage I patients, and 34.4, 31.8, and 52% for stage II to IV patients, respectively. The percentage of caregivers who stopped working was 13.6%. The EQ-5D index was strongly associated with the dyspnea scale (r = –0.64, p < 0.001). The average required time to see a doctor and visit the pharmacy was 154 minutes. Conclusions: In patients with COPD, the EQ-5D index decreased and disease-related home caregiving increased with airflow limitation. We considered the caregiver-related burden when making a strategy for COPD management.

Original languageEnglish
Pages (from-to)1136-1144
Number of pages9
JournalKorean Journal of Internal Medicine
Issue number5
StatePublished - 2020

Bibliographical note

Publisher Copyright:
© 2020 The Korean Association of Internal Medicine.


  • Caregivers
  • Health expenditures
  • Pulmonary disease, chronic obstructive
  • Quality of life


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