The effects of simultaneous combined exposure to CDMA and WCDMA electromagnetic fields on rat testicular function

Hae June Lee, Yeung Bae Jin, Tae Hong Kim, Jeong Ki Pack, Nam Kim, Hyung Do Choi, Jae Seon Lee, Yun Sil Lee

Research output: Contribution to journalArticlepeer-review

34 Scopus citations

Abstract

Wireless mobile phones and other telecommunication devices are used extensively in daily life. We therefore examined the effects of combined exposure to radiofrequency electromagnetic fields (RF-EMF) on rat testicular function, specifically with respect to sensitive processes such as spermatogenesis. Male rats were exposed to single code division multiple access (CDMA) and wideband code division multiple access (WCDMA) RF signals for 12 weeks. The RF exposure schedule comprised 45min/day, 5 days/week for a total of 12 weeks. The whole-body average specific absorption rate (SAR) of CDMA and WCDMA was 2.0W/kg each or 4.0W/kg in total. We then investigated the correlates of testicular function such as sperm count in the cauda epididymis, testosterone concentration in the blood serum, malondialdehyde concentrations in the testes and epididymis, frequency of spermatogenesis stages, and appearance of apoptotic cells in the testes. We also immunoblotted for p53, bcl2, GADD45, cyclin G, and HSP70 in the testes of sham- and combined RF-exposed animals. Based on the results, we concluded that simultaneous exposure to CDMA and WCDMA RF-EMFs at 4.0W/kg SAR did not have any observable adverse effects on rat spermatogenesis.

Original languageEnglish
Pages (from-to)356-364
Number of pages9
JournalBioelectromagnetics
Volume33
Issue number4
DOIs
StatePublished - May 2012

Keywords

  • CDMA
  • Combined RF exposure
  • Rat spermatogenesis
  • WCDMA

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