TY - JOUR
T1 - The effect of polydeoxyribonucleotide on chronic non-healing wound of an amputee
T2 - A case report
AU - Shin, Junho
AU - Park, Gahee
AU - Lee, Junhee
AU - Bae, Hasuk
N1 - Publisher Copyright:
© 2018 by Korean Academy of Rehabilitation Medicine.
PY - 2018/8/1
Y1 - 2018/8/1
N2 - Polydeoxyribonucleotide (PDRN) is safe and effective in wound healing, cellular growth, synthesis of extracellular matrix protein, and inflammation reduction via activation of adenosine A2 receptors. We report a 28-year-old male patient treated with PDRN injections for chronic non-healing wound refractory to negative pressure wound therapy, skin graft, or growth factors. Three injections of PDRN were administered at the wound site into the anterior and medial sides of the left stump on the 1st, 4th, and 9th days of hospitalization. The PDRN ameliorated wound healing by enhancing cell growth, tissue repair, and angiogenesis. PDRN application represents a potential treatment for non-healing wounds obviating the need for additional therapies, and hospitalization, as well as improve patient's activities of daily living.
AB - Polydeoxyribonucleotide (PDRN) is safe and effective in wound healing, cellular growth, synthesis of extracellular matrix protein, and inflammation reduction via activation of adenosine A2 receptors. We report a 28-year-old male patient treated with PDRN injections for chronic non-healing wound refractory to negative pressure wound therapy, skin graft, or growth factors. Three injections of PDRN were administered at the wound site into the anterior and medial sides of the left stump on the 1st, 4th, and 9th days of hospitalization. The PDRN ameliorated wound healing by enhancing cell growth, tissue repair, and angiogenesis. PDRN application represents a potential treatment for non-healing wounds obviating the need for additional therapies, and hospitalization, as well as improve patient's activities of daily living.
KW - Amputees
KW - Polydeoxyribonucleotides
KW - Wound healing
UR - http://www.scopus.com/inward/record.url?scp=85052790579&partnerID=8YFLogxK
U2 - 10.5535/arm.2018.42.4.630
DO - 10.5535/arm.2018.42.4.630
M3 - Article
AN - SCOPUS:85052790579
VL - 42
SP - 630
EP - 633
JO - Annals of Rehabilitation Medicine
JF - Annals of Rehabilitation Medicine
SN - 2234-0645
IS - 4
ER -