The Effect of Dexmedetomidine on the Mini-Cog Score and High-Mobility Group Box 1 Levels in Elderly Patients with Postoperative Neurocognitive Disorders Undergoing Orthopedic Surgery

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Dexmedetomidine prevents postoperative cognitive dysfunction by inhibiting high-mobility group box 1 (HMGB1), which acts as an inflammatory marker.

Original languageEnglish
Article number6610
JournalJournal of Clinical Medicine
Volume12
Issue number20
DOIs
StatePublished - Oct 2023

Bibliographical note

Publisher Copyright:
© 2023 by the authors.

Keywords

  • HMGB1
  • Mini-Cog
  • aged
  • dexmedetomidine
  • neurocognitive disorders
  • orthopedic surgery
  • postoperative cognitive complications

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