Tandem blaise-alkenylation with unactivated alkynes: One-pot synthesis of α-vinylated β-enaminoesters from nitriles

Yu Sung Chun, Young Ok Ko, Hyunik Shin, Sang Gi Lee

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

The in situ generated Blaise reaction intermediate, a zinc bromide complex of β-enaminoester, reacts with various unactivated terminal alkynes and an internal alkyne under mild conditions to afford α-vinylated β-enaminoesters in good to excellent yields.

Original languageEnglish
Pages (from-to)3414-3417
Number of pages4
JournalOrganic Letters
Volume11
Issue number15
DOIs
StatePublished - 6 Aug 2009

Fingerprint

Dive into the research topics of 'Tandem blaise-alkenylation with unactivated alkynes: One-pot synthesis of α-vinylated β-enaminoesters from nitriles'. Together they form a unique fingerprint.

Cite this