Systemic lupus erythematosus associated with interstitial pneumonia and achalasia

Lee Kwon Hye, Wook Hong Kyung, Jin Lim Seung, Young Park So, Deok Bae Young, Ho Kim Kyung, Hee Choi Jeong, Kyung Mo Eun, Bum Park Yong

Research output: Contribution to journalArticlepeer-review


Systemic lupus erythematosus (SLE) is a multisystem disorder where the etiology is not clearly known. Symptomatic chronic interstitial pneumonitis is an uncommon manifestation, with a reported prevalence of 3-13%. Achalasia is rare disease that presents with failure in the relaxation of the esophagus sphincter. A 22-year-old woman was admitted to our hospital because of fever, cough and dyspnea. The patient had a history of pericardial effusion and Raynaud's phenomenon. The results of laboratory tests indicated the presence of lymphopenia and included positive antibody tests for antinuclear antibody and anti Sm antibody. A chest X-ray demonstrated the presence of peribronchial infiltration on both lung fields. A Chest CT image showed interlobar septal thickening, ground-glass opacity and a honeycomb appearance in both lung fields and esophageal dilatation with air fluid level. An esophagogram showed the presence of dilated esophagus ends that represented the non-relaxed lower esophageal sphincter. Manometry demonstrated incomplete sphincter relaxation. The case was diagnosed as systemic lupus erythematosus associated with interstitial pneumonia and achalasia.

Original languageEnglish
Pages (from-to)323-327
Number of pages5
JournalTuberculosis and Respiratory Diseases
Issue number4
StatePublished - Oct 2008


  • Achalasia
  • Interstitial pneumonia
  • SLE


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