Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of rigid analogues of 2,4,6-trisubstituted pyridine containing 5,6-dihydrobenzo[h]quinoline moiety

Byeong Seon Jeong; Hoyoung Choi; Pritam Thapa; Radha Karki; Eunyoung Lee; Jung Min Nam; Younghwa Na; Eun Mi Ha; Youngjoo Kwon; Eung Seok Lee

doi:10.5012/bkcs.2011.32.1.303

Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of rigid analogues of 2,4,6-trisubstituted pyridine containing 5,6-dihydrobenzo[h]quinoline moiety

Byeong Seon Jeong
, Hoyoung Choi
, Pritam Thapa
, Radha Karki
, Eunyoung Lee
, Jung Min Nam
, Younghwa Na
, Eun Mi Ha
, Youngjoo Kwon
, Eung Seok Lee

Department of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Original language	English
Pages (from-to)	303-306
Number of pages	4
Journal	Bulletin of the Korean Chemical Society
Volume	32
Issue number	1
DOIs	https://doi.org/10.5012/bkcs.2011.32.1.303
State	Published - 20 Jan 2011

Keywords

2,4,6-Trisubstituted pyridine
5,6-Dihydrobenzo[h]quinoline
Cytotoxicity
Rigid analog
Topoisomerase inhibitor

Access to Document

10.5012/bkcs.2011.32.1.303

Cite this

Jeong, B. S., Choi, H., Thapa, P., Karki, R., Lee, E., Nam, J. M., Na, Y., Ha, E. M., Kwon, Y., & Lee, E. S. (2011). Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of rigid analogues of 2,4,6-trisubstituted pyridine containing 5,6-dihydrobenzo[h]quinoline moiety. Bulletin of the Korean Chemical Society, 32(1), 303-306. https://doi.org/10.5012/bkcs.2011.32.1.303

@article{76ecb3614aab4a03a1cf809b3b66cf34,

title = "Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of rigid analogues of 2,4,6-trisubstituted pyridine containing 5,6-dihydrobenzo[h]quinoline moiety",

keywords = "2,4,6-Trisubstituted pyridine, 5,6-Dihydrobenzo[h]quinoline, Cytotoxicity, Rigid analog, Topoisomerase inhibitor",

author = "Jeong, \{Byeong Seon\} and Hoyoung Choi and Pritam Thapa and Radha Karki and Eunyoung Lee and Nam, \{Jung Min\} and Younghwa Na and Ha, \{Eun Mi\} and Youngjoo Kwon and Lee, \{Eung Seok\}",

year = "2011",

month = jan,

day = "20",

doi = "10.5012/bkcs.2011.32.1.303",

language = "English",

volume = "32",

pages = "303--306",

journal = "Bulletin of the Korean Chemical Society",

issn = "0253-2964",

publisher = "Wiley-Blackwell",

number = "1",

}

Jeong, BS, Choi, H, Thapa, P, Karki, R, Lee, E, Nam, JM, Na, Y, Ha, EM, Kwon, Y & Lee, ES 2011, 'Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of rigid analogues of 2,4,6-trisubstituted pyridine containing 5,6-dihydrobenzo[h]quinoline moiety', Bulletin of the Korean Chemical Society, vol. 32, no. 1, pp. 303-306. https://doi.org/10.5012/bkcs.2011.32.1.303

Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of rigid analogues of 2,4,6-trisubstituted pyridine containing 5,6-dihydrobenzo[h]quinoline moiety. / Jeong, Byeong Seon; Choi, Hoyoung; Thapa, Pritam et al.
In: Bulletin of the Korean Chemical Society, Vol. 32, No. 1, 20.01.2011, p. 303-306.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of rigid analogues of 2,4,6-trisubstituted pyridine containing 5,6-dihydrobenzo[h]quinoline moiety

AU - Jeong, Byeong Seon

AU - Choi, Hoyoung

AU - Thapa, Pritam

AU - Karki, Radha

AU - Lee, Eunyoung

AU - Nam, Jung Min

AU - Na, Younghwa

AU - Ha, Eun Mi

AU - Kwon, Youngjoo

AU - Lee, Eung Seok

PY - 2011/1/20

Y1 - 2011/1/20

KW - 2,4,6-Trisubstituted pyridine

KW - 5,6-Dihydrobenzo[h]quinoline

KW - Cytotoxicity

KW - Rigid analog

KW - Topoisomerase inhibitor

UR - https://www.scopus.com/pages/publications/78951477341

U2 - 10.5012/bkcs.2011.32.1.303

DO - 10.5012/bkcs.2011.32.1.303

M3 - Article

AN - SCOPUS:78951477341

SN - 0253-2964

VL - 32

SP - 303

EP - 306

JO - Bulletin of the Korean Chemical Society

JF - Bulletin of the Korean Chemical Society

IS - 1

ER -