Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of rigid analogues of 2,4,6-trisubstituted pyridine containing 5,6-dihydrobenzo[h]quinoline moiety

Byeong Seon Jeong; Hoyoung Choi; Pritam Thapa; Radha Karki; Eunyoung Lee; Jung Min Nam; Younghwa Na; Eun Mi Ha; Youngjoo Kwon; Eung Seok Lee

doi:10.5012/bkcs.2011.32.1.303

Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of rigid analogues of 2,4,6-trisubstituted pyridine containing 5,6-dihydrobenzo[h]quinoline moiety

Byeong Seon Jeong, Hoyoung Choi, Pritam Thapa, Radha Karki, Eunyoung Lee, Jung Min Nam, Younghwa Na, Eun Mi Ha, Youngjoo Kwon, Eung Seok Lee

Department of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Original language	English
Pages (from-to)	303-306
Number of pages	4
Journal	Bulletin of the Korean Chemical Society
Volume	32
Issue number	1
DOIs	https://doi.org/10.5012/bkcs.2011.32.1.303
State	Published - 20 Jan 2011

Keywords

2,4,6-Trisubstituted pyridine
5,6-Dihydrobenzo[h]quinoline
Cytotoxicity
Rigid analog
Topoisomerase inhibitor

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10.5012/bkcs.2011.32.1.303

Cite this

Jeong, B. S., Choi, H., Thapa, P., Karki, R., Lee, E., Nam, J. M., Na, Y., Ha, E. M., Kwon, Y., & Lee, E. S. (2011). Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of rigid analogues of 2,4,6-trisubstituted pyridine containing 5,6-dihydrobenzo[h]quinoline moiety. Bulletin of the Korean Chemical Society, 32(1), 303-306. https://doi.org/10.5012/bkcs.2011.32.1.303

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title = "Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of rigid analogues of 2,4,6-trisubstituted pyridine containing 5,6-dihydrobenzo[h]quinoline moiety",

keywords = "2,4,6-Trisubstituted pyridine, 5,6-Dihydrobenzo[h]quinoline, Cytotoxicity, Rigid analog, Topoisomerase inhibitor",

author = "Jeong, {Byeong Seon} and Hoyoung Choi and Pritam Thapa and Radha Karki and Eunyoung Lee and Nam, {Jung Min} and Younghwa Na and Ha, {Eun Mi} and Youngjoo Kwon and Lee, {Eung Seok}",

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language = "English",

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Jeong, BS, Choi, H, Thapa, P, Karki, R, Lee, E, Nam, JM, Na, Y, Ha, EM, Kwon, Y & Lee, ES 2011, 'Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of rigid analogues of 2,4,6-trisubstituted pyridine containing 5,6-dihydrobenzo[h]quinoline moiety', Bulletin of the Korean Chemical Society, vol. 32, no. 1, pp. 303-306. https://doi.org/10.5012/bkcs.2011.32.1.303

Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of rigid analogues of 2,4,6-trisubstituted pyridine containing 5,6-dihydrobenzo[h]quinoline moiety. / Jeong, Byeong Seon; Choi, Hoyoung; Thapa, Pritam et al.
In: Bulletin of the Korean Chemical Society, Vol. 32, No. 1, 20.01.2011, p. 303-306.

Research output: Contribution to journal › Article › peer-review

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AU - Jeong, Byeong Seon

AU - Choi, Hoyoung

AU - Thapa, Pritam

AU - Karki, Radha

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AU - Nam, Jung Min

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AU - Ha, Eun Mi

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AU - Lee, Eung Seok

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