Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of rigid analogues of 2,4,6-trisubstituted pyridine containing 5,6-dihydrobenzo[h]quinoline moiety

Byeong Seon Jeong, Hoyoung Choi, Pritam Thapa, Radha Karki, Eunyoung Lee, Jung Min Nam, Younghwa Na, Eun Mi Ha, Youngjoo Kwon, Eung Seok Lee

Research output: Contribution to journalArticlepeer-review

25 Scopus citations
Original languageEnglish
Pages (from-to)303-306
Number of pages4
JournalBulletin of the Korean Chemical Society
Issue number1
StatePublished - 20 Jan 2011


  • 2,4,6-Trisubstituted pyridine
  • 5,6-Dihydrobenzo[h]quinoline
  • Cytotoxicity
  • Rigid analog
  • Topoisomerase inhibitor

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