Synthesis of phosphoramidates: A facile approach based on the C-N bond formation via Ir-catalyzed direct C-H amidation

Hyunwoo Kim; Juhyeon Park; Jeung Gon Kim; Sukbok Chang

doi:10.1021/ol502722j

Synthesis of phosphoramidates: A facile approach based on the C-N bond formation via Ir-catalyzed direct C-H amidation

Hyunwoo Kim, Juhyeon Park, Jeung Gon Kim, Sukbok Chang

Department of Chemistry & Nanoscience

Research output: Contribution to journal › Article › peer-review

72 Scopus citations

Abstract

A new synthetic route to phosphoramidates by intermolecular C-H amidation is presented. Substrates with assorted directing groups were activated by an iridium-based catalyst system and reacted with a number of phosphoryl azides, executing efficient phosphoramidate synthesis via C-N bond formations. (Chemical Equation Presented).

Original language	English
Pages (from-to)	5466-5469
Number of pages	4
Journal	Organic Letters
Volume	16
Issue number	20
DOIs	https://doi.org/10.1021/ol502722j
State	Published - 17 Oct 2014

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© 2014 American Chemical Society.

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title = "Synthesis of phosphoramidates: A facile approach based on the C-N bond formation via Ir-catalyzed direct C-H amidation",

abstract = "A new synthetic route to phosphoramidates by intermolecular C-H amidation is presented. Substrates with assorted directing groups were activated by an iridium-based catalyst system and reacted with a number of phosphoryl azides, executing efficient phosphoramidate synthesis via C-N bond formations. (Chemical Equation Presented).",

author = "Hyunwoo Kim and Juhyeon Park and Kim, {Jeung Gon} and Sukbok Chang",

note = "Publisher Copyright: {\textcopyright} 2014 American Chemical Society.",

year = "2014",

month = oct,

day = "17",

doi = "10.1021/ol502722j",

language = "English",

volume = "16",

pages = "5466--5469",

journal = "Organic Letters",

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T2 - A facile approach based on the C-N bond formation via Ir-catalyzed direct C-H amidation

AU - Kim, Hyunwoo

AU - Park, Juhyeon

AU - Kim, Jeung Gon

AU - Chang, Sukbok

PY - 2014/10/17

Y1 - 2014/10/17

N2 - A new synthetic route to phosphoramidates by intermolecular C-H amidation is presented. Substrates with assorted directing groups were activated by an iridium-based catalyst system and reacted with a number of phosphoryl azides, executing efficient phosphoramidate synthesis via C-N bond formations. (Chemical Equation Presented).

AB - A new synthetic route to phosphoramidates by intermolecular C-H amidation is presented. Substrates with assorted directing groups were activated by an iridium-based catalyst system and reacted with a number of phosphoryl azides, executing efficient phosphoramidate synthesis via C-N bond formations. (Chemical Equation Presented).

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U2 - 10.1021/ol502722j

DO - 10.1021/ol502722j

M3 - Article

AN - SCOPUS:84908063025

SN - 1523-7060

VL - 16

SP - 5466

EP - 5469

JO - Organic Letters

JF - Organic Letters

IS - 20

ER -

Synthesis of phosphoramidates: A facile approach based on the C-N bond formation via Ir-catalyzed direct C-H amidation

Abstract

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