@article{70b0fbbf80d6411a88cad6a600af1ee2,
title = "Synthesis of novel thiol taxoids based on the 7,10-di-(2,2,2- trichloroethyloxycarbonyl)-10-deacetylbaccatin III: Both the syn and anti 10-deacetyl-2′-deoxy-2′-mercaptopaclitaxels",
abstract = "Two new kinds of docetaxel compound, with a mercapto group instead of the hydroxyl on the C13 side chain (both syn and anti), via the 7,10-di-(2,2,2- trichloroethyloxycarbonyl)-10-deacetylbaccatin III route, were synthesized. The uses of trans and cis oxazoline compounds, and their stereoselective ring-opening reactions with thiolacetic acid, were proved to be key steps.",
keywords = "Mercapto taxoid, Oxazoline, Taxol",
author = "Xin Qi and Lee, {Sang Hyeup} and Juyoung Yoon and Lee, {Yoon Sik}",
note = "Funding Information: We thank Hanmi Pharmaceutical Co., Ltd for the generous donation of 10-deacetylbaccatin III. This work was supported by Korea Science and Engineering Foundation (R14-2003-014-01001-0) and the Brain Korea 21 Program.",
year = "2004",
month = may,
day = "3",
doi = "10.1016/j.tet.2004.03.064",
language = "English",
volume = "60",
pages = "4133--4138",
journal = "Tetrahedron",
issn = "0040-4020",
publisher = "Elsevier Ltd.",
number = "19",
}