Synthesis of 1‐alkoxy‐5‐alkyluracils

Dae‐Kee ‐K Kim, Ganghyeok Kim, Jinsoo Lim, Key H. Kim

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1‐Alkoxy‐5‐alkyluracils 2a‐f have been prepared by the reaction of 2‐alkyl‐3‐methoxyacryloyl isocyanates 8a‐b with alkoxyamines 9a‐c followed by cyclization of the resulting N‐alkoxy‐N'‐(2‐alkyl‐3‐methoxyacryloyl)ureas 10a‐f. The isocyanates 8a‐b were prepared from ethyl 2‐alkylacrylates 3a‐b in 5 steps.

Original languageEnglish
Pages (from-to)1625-1629
Number of pages5
JournalJournal of Heterocyclic Chemistry
Issue number5
StatePublished - 1995


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