Synthesis and biological activity of optically active phenylbutenoid dimers

Jeonghyun Chu; Dong Hoon Suh; Gehyung Lee; Ah Reum Han; Song Wha Chae; Hwa Jeong Lee; Eun Kyoung Seo; Hee Jong Lim

doi:10.1021/np100942e

Synthesis and biological activity of optically active phenylbutenoid dimers

Jeonghyun Chu
, Dong Hoon Suh
, Gehyung Lee
, Ah Reum Han
, Song Wha Chae
, Hwa Jeong Lee
, Eun Kyoung Seo
, Hee Jong Lim

Department of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

The total synthesis of optically active phenylbutenoid dimers 1, 3, and ent-3 is described. The key step to access optically active cyclohexene rings was achieved by Diels-Alder reaction of chiral acryloyloxazolinone 9 and phenylbetadiene 10.

Original language	English
Pages (from-to)	1817-1821
Number of pages	5
Journal	Journal of Natural Products
Volume	74
Issue number	8
DOIs	https://doi.org/10.1021/np100942e
State	Published - 26 Aug 2011

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10.1021/np100942e

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@article{c45b9e4fc1204444b0f8474f557d135d,

title = "Synthesis and biological activity of optically active phenylbutenoid dimers",

abstract = "The total synthesis of optically active phenylbutenoid dimers 1, 3, and ent-3 is described. The key step to access optically active cyclohexene rings was achieved by Diels-Alder reaction of chiral acryloyloxazolinone 9 and phenylbetadiene 10.",

author = "Jeonghyun Chu and Suh, \{Dong Hoon\} and Gehyung Lee and Han, \{Ah Reum\} and Chae, \{Song Wha\} and Lee, \{Hwa Jeong\} and Seo, \{Eun Kyoung\} and Lim, \{Hee Jong\}",

year = "2011",

month = aug,

day = "26",

doi = "10.1021/np100942e",

language = "English",

volume = "74",

pages = "1817--1821",

journal = "Journal of Natural Products",

issn = "0163-3864",

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TY - JOUR

T1 - Synthesis and biological activity of optically active phenylbutenoid dimers

AU - Chu, Jeonghyun

AU - Suh, Dong Hoon

AU - Lee, Gehyung

AU - Han, Ah Reum

AU - Chae, Song Wha

AU - Lee, Hwa Jeong

AU - Seo, Eun Kyoung

AU - Lim, Hee Jong

PY - 2011/8/26

Y1 - 2011/8/26

N2 - The total synthesis of optically active phenylbutenoid dimers 1, 3, and ent-3 is described. The key step to access optically active cyclohexene rings was achieved by Diels-Alder reaction of chiral acryloyloxazolinone 9 and phenylbetadiene 10.

AB - The total synthesis of optically active phenylbutenoid dimers 1, 3, and ent-3 is described. The key step to access optically active cyclohexene rings was achieved by Diels-Alder reaction of chiral acryloyloxazolinone 9 and phenylbetadiene 10.

UR - https://www.scopus.com/pages/publications/80052183135

U2 - 10.1021/np100942e

DO - 10.1021/np100942e

M3 - Article

C2 - 21770432

AN - SCOPUS:80052183135

SN - 0163-3864

VL - 74

SP - 1817

EP - 1821

JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 8

ER -

Synthesis and biological activity of optically active phenylbutenoid dimers

Abstract

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