Synthesis and biological activity of optically active phenylbutenoid dimers

Jeonghyun Chu; Dong Hoon Suh; Gehyung Lee; Ah Reum Han; Song Wha Chae; Hwa Jeong Lee; Eun Kyoung Seo; Hee Jong Lim

doi:10.1021/np100942e

Synthesis and biological activity of optically active phenylbutenoid dimers

Jeonghyun Chu, Dong Hoon Suh, Gehyung Lee, Ah Reum Han, Song Wha Chae, Hwa Jeong Lee, Eun Kyoung Seo, Hee Jong Lim

Department of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

The total synthesis of optically active phenylbutenoid dimers 1, 3, and ent-3 is described. The key step to access optically active cyclohexene rings was achieved by Diels-Alder reaction of chiral acryloyloxazolinone 9 and phenylbetadiene 10.

Original language	English
Pages (from-to)	1817-1821
Number of pages	5
Journal	Journal of Natural Products
Volume	74
Issue number	8
DOIs	https://doi.org/10.1021/np100942e
State	Published - 26 Aug 2011

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10.1021/np100942e

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@article{c45b9e4fc1204444b0f8474f557d135d,

title = "Synthesis and biological activity of optically active phenylbutenoid dimers",

abstract = "The total synthesis of optically active phenylbutenoid dimers 1, 3, and ent-3 is described. The key step to access optically active cyclohexene rings was achieved by Diels-Alder reaction of chiral acryloyloxazolinone 9 and phenylbetadiene 10.",

author = "Jeonghyun Chu and Suh, \{Dong Hoon\} and Gehyung Lee and Han, \{Ah Reum\} and Chae, \{Song Wha\} and Lee, \{Hwa Jeong\} and Seo, \{Eun Kyoung\} and Lim, \{Hee Jong\}",

year = "2011",

month = aug,

day = "26",

doi = "10.1021/np100942e",

language = "English",

volume = "74",

pages = "1817--1821",

journal = "Journal of Natural Products",

issn = "0163-3864",

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TY - JOUR

T1 - Synthesis and biological activity of optically active phenylbutenoid dimers

AU - Chu, Jeonghyun

AU - Suh, Dong Hoon

AU - Lee, Gehyung

AU - Han, Ah Reum

AU - Chae, Song Wha

AU - Lee, Hwa Jeong

AU - Seo, Eun Kyoung

AU - Lim, Hee Jong

PY - 2011/8/26

Y1 - 2011/8/26

N2 - The total synthesis of optically active phenylbutenoid dimers 1, 3, and ent-3 is described. The key step to access optically active cyclohexene rings was achieved by Diels-Alder reaction of chiral acryloyloxazolinone 9 and phenylbetadiene 10.

AB - The total synthesis of optically active phenylbutenoid dimers 1, 3, and ent-3 is described. The key step to access optically active cyclohexene rings was achieved by Diels-Alder reaction of chiral acryloyloxazolinone 9 and phenylbetadiene 10.

UR - https://www.scopus.com/pages/publications/80052183135

U2 - 10.1021/np100942e

DO - 10.1021/np100942e

M3 - Article

C2 - 21770432

AN - SCOPUS:80052183135

SN - 0163-3864

VL - 74

SP - 1817

EP - 1821

JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 8

ER -

Synthesis and biological activity of optically active phenylbutenoid dimers

Abstract

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