Surgical management of mechanical valve thrombosis: Twenty-six years' experience

Hyuk Ahn, Kyung Hwan Kim, Chang Kim Kwan, Young Kim Chang

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


In the present study, the authors investigated the management of mechanical valve thrombosis (MVT). From January 1981 through March 2006, 2,908 mechanical valve replacements were performed in 2,298 patients at our institution. Twenty (0.87%) patients presented with MVT, 14 (70.0%) were women, and the mean age of the patients was 42.0±14.0 (27-66) yr. Thrombosis involved mitral in 14 (70.0%), aortic in 2 (10.0%), tricuspid/aortic in 1 (5%), and tricuspid in 3 (15%). The interval from first operation to valve thrombosis was 121.8±75.4 (0.9-284.7) months. The most frequent clinical presentation was heart failure (13/20, 65%), and predisposing causes of MVT were: poor compliance with warfarin (7), pregnancy (5), drug interaction (2), and unknown (6). All 20 patients underwent valve replacement: mitral (14, 70.0%), tricuspid (3, 15.0%), aortic (2, 10%) and tricuspid/aortic (1, 5%). One early death occurred due to left ventricular failure, but no late mortality occurred during 63.3±49.9 (0.5-165.1) months of follow-up. MVT was treated successfully, and pregnancy and inadequate anticoagulation were found to influence the occurrence of this rare complication.

Original languageEnglish
Pages (from-to)378-382
Number of pages5
JournalJournal of Korean Medical Science
Issue number3
StatePublished - Jun 2008


  • Heart valves
  • Mechanical valve
  • Thrombosis


Dive into the research topics of 'Surgical management of mechanical valve thrombosis: Twenty-six years' experience'. Together they form a unique fingerprint.

Cite this