Easy trap-and-release of microparticles is necessary to study biological cellular behavior. The hydraulic jump phenomenon inspired us to conceive a microfluidic device for the hydrodynamic trap-and-release of microparticles. A sudden height increase in a microfluidic channel leads to a dramatic decrease in flow velocity, allowing effective trapping of the microparticles by energy conversion. The trapped particles can be released by stronger inertial force based on simply increasing the flow velocity. We present a systematic, numerical study of trap-and-release of the microparticles using multiphase Navier-Stokes equations. Effect of geometry flow velocity, particle diameter, and adhesion force on trap-and-release was studied.
Bibliographical noteFunding Information:
The authors acknowledge the funding from the National Institutes of Health (Grant No. R01 CA120003-01A2) and the Center for Nanostructured Materials Technology (Grant Nos. 2010K000352, 2010K000353, and 2010K000354) under “21st Century Frontier R&D Programs” of the Ministry of Education, Science and Technology, Korea. Three of authors Y.P., Y.C., and D.M. contributed equally to this work.