Structural requirements of 1-(2-pyridinyl)-5-pyrazolones for disproportionation of boronic acids

Joungmo Cho, Venkata Subbaiah Sadu, Yohan Han, Yunsoo Bae, Hwajeong Lee, Kee In Lee

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2 Scopus citations


We observed an unusual formation of four-coordinate boron(III) complexes from the reaction of 1-(2-pyridinyl)-5-pyrazolone derivatives with arylboronic acids in the basic media. The exact mechanism is not clear; however, the use of unprotected boronic acid and the presence of a bidentate ligand appeared to be the key structural requirements for the transformation. The results suggest that base-promoted disproportionation of arylboronic acid with the assistance of the [N,O]-bidentate ligation of 1-(2-pyridinyl)-5-pyrazolone should take place and facilitate the formation of pyrazole di-arylborinate. Experiments to obtain a deeper understanding of its mechanism are currently underway.

Original languageEnglish
Article number6814
Issue number22
StatePublished - 2 Nov 2021

Bibliographical note

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© 2021 by the authors. Licensee MDPI, Basel, Switzerland.


  • 1-(2-pyridinyl)-5-pyrazolone
  • Arylboronic acid
  • Base
  • Diarylbori-nation
  • Four-coordinate boron(III) complex
  • [N,O]-bidentate ligand


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