Structural optimization and biological evaluation of ML364 based derivatives as USP2a inhibitors

Biochemistry, Genetics and Molecular Biology

• Ubiquitin 100%
• Deubiquitinating Enzyme 50%
• Protein Catabolism 50%
• Posttranslational Modification 50%
• Cancer Cell 50%
• Ubiquitination 50%
• Enzyme Active Site 50%
• Carcinogenesis 50%
• Cell Growth 50%
• Cytotoxicity 50%
• USP7 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Ubiquitin 100%
• Deubiquitinase 50%
• Cancer Growth 50%
• Carcinogenesis 50%
• Ubiquitin Carboxyl Terminal Hydrolase 7 50%
• Cytotoxicity 50%