Strategies for nanoplasmonic core-satellite biomolecular sensors: Theory-based Design

Benjamin M. Ross, John R. Waldeisen, Tim Wang, Luke P. Lee

Research output: Contribution to journalArticlepeer-review

42 Scopus citations


We present a systematic theoretical study of core-satellite gold nanoparticle assemblies using the Generalized Multiparticle Mie formalism. We consider the importance of satellite number, satellite radius, the core radius, and the satellite distance, and we present approaches to optimize spectral shift due to satellite attachment or release. This provides clear strategies for improving the sensitivity and signal-to-noise ratio for molecular detection, enabling simple colorimetric assays. We quantify the performance of these strategies by introducing a figure of merit. In addition, we provide an improved understanding of the nanoplasmonic interactions that govern the optical response of core-satellite nanoassemblies.

Original languageEnglish
Article number193112
JournalApplied Physics Letters
Issue number19
StatePublished - 2009

Bibliographical note

Funding Information:
The authors thank Yu-lin Xu for making his GMM Fortran code publicly available; this code was used in this letter. J.R.W. acknowledges support from an NSF graduate research fellowship. The authors acknowledge financial support from National Institutes of Health (NIH) Nanomedicine Development Centers funding (Grant No. 3PN2 EY01824), National Academies Keck Futures Initiative funding (Grant No. NAKFI Nano09), and DARPA MF3 Award No. HR0011-06-1-0050.


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