Abstract
Stereoselective synthesis of d-5-homo-4-selenoribose, serving as a versatile intermediate for the synthesis of 4′-selenonucleosides 12a-c, was accomplished using Sharpless asymmetric epoxidation, regioselective cleavage of the α,β-epoxide, and stereoselective reduction of the ketone as the key steps.
Original language | English |
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Pages (from-to) | 4636-4639 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 17 |
Issue number | 18 |
DOIs | |
State | Published - 18 Sep 2015 |