Standardized Rhus verniciflua stokes extract and its major flavonoid fustin attenuate oxidative stress induced by tert-butyl hydroperoxide via activation of nuclear factor erythroid 2-related factor

Ye Jin Choi, Gyeong Min Do, Jae Ho Shin, Ji Yeon Kim, Oran Kwon

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

The antioxidant effects of an urushiol-free standardized Rhus verniciflua Stokes (RVS) extract and fustin were investigated using oxidative stress-induced rats by tert-butyl hydroperoxide (t-BHP). Hepatic glutathione levels were higher in RVS and fustin groups than those of the t-BHP treated control group. The level of hepatic nuclear factor erythroid 2-related factor was increased by RVS and fustin. The histology results indicated that rats fed RVS had a lower rate of necrosis than the control rats injected with t-BHP.

Original languageEnglish
Pages (from-to)27-30
Number of pages4
JournalJournal of the Korean Society for Applied Biological Chemistry
Volume57
Issue number1
DOIs
StatePublished - Feb 2014

Keywords

  • fustin
  • glutathione
  • nuclear factor erythroid 2 related factor
  • Rhus verniciflua Stokes
  • tert-butyl hydroperoxide

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