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Squamous Cell Carcinoma In Situ Originating From Nasal Polyps With Human Papillomavirus 51 Infection: A Case Report

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Abstract

Malignant transformation of nasal polyps is extremely rare in cases without background inverted papilloma. Human papillomavirus (HPV) is a sexually transmitted infection believed to be associated with oropharyngeal carcinoma via oro-genital sexual contact. We present a case of focal squamous cell carcinoma in situ that occurred on the surface of nasal polyps and was associated with HPV 51. The patient was successfully treated with endoscopic sinus surgery. Clinicians should be aware of the potential for hidden malignancies, and pathologic assessment of tissue specimens must be performed even in simple nasal polyp cases.

Original languageEnglish
Pages (from-to)1054S-1057S
JournalEar, Nose and Throat Journal
Volume100
Issue number10_suppl
DOIs
StatePublished - Dec 2021

Bibliographical note

Publisher Copyright:
© The Author(s) 2020.

Keywords

  • carcinoma in situ
  • HPV 51 genotype
  • human papilloma virus (HPV)
  • malignant transformation
  • nasal polyp
  • squamous cell carcinoma

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