Speed-of-sound Estimation of Dual-acoustic Waves using Laser-activated Nanodroplets

A coherency of photoacoustic and ultrasound waves is dependent on the accuracy of the speedof- sound. This study evaluates the feasibility of a speed-of-sound estimation method for dual photoacoustic and ultrasound waves using laser-activated phase-change perfluorohexane nanodroplets (PFHnDs). The proposed method demonstrates that the estimated speed-of-sound (ESS) is close to the expected speed-of-sound for the medium (deviation = 0.3%), so it is useful for phase aberration correction in dual ultrasound and photoacoustic imaging.